中文摘要：

目的 研究早中期肝癌患者疾病感知（对自身疾病的认知和情绪反应）与生活质量的相关性。方法 对2015年1-12月入住第三军医大学西南医院肝脏外科的早中期肝癌患者,以癌症患者生活质量量表和疾病感知量表进行测评,多元线性回归分析在人口统计学、社会支持和应对方式等影响因素共同存在的情况下,疾病感知与生活质量的相关性。结果 共220例患者纳入本研究。多元线性回归分析结果显示,男性患者的总体生活质量平均分显著高于女性患者（P〈0.001）,疾病感知中的自我对疾病的控制力（β=1.707,P=0.003）、感知的症状大小（β=-1.315,P=0.016）、对疾病的了解程度（β=1.489,P=0.014）与总体生活质量具有相关性。结论 早中期肝癌患者对疾病的控制力、感知的症状大小以及对疾病的了解程度影响其生活质量。

英文摘要：

Objective To determine the association of patients＇ illness perceptions （awareness and emotional response to their own diseases） and the health-related quality of life （HRQOL） in the patients with early- and intermediate-stage hepatocellular carcinoma （HCC）. Methods The early- and intermediate-stage HCC patients admitted for potentially curative treatments in the Southwest Hospital from January to December 2015 were recruited in this study. The patients were interviewed at admission for HRQOL, illness perceptions, coping style and social support. Multivariate linear regression analysis was performed to determine the variables which were significantly related to the global HRQOL. Results Totally 220 patients were subjected in this study. Multivariate linear regression analysis showed that the mean score of quality of life was obviously higher in the male patients than the female patients （P 〈 0. 001 ）. In regard to illness perceptions, personal control （β= 1. 707, P = 0. 003）, identity of symptoms （β= - 1. 315, P = 0. 016） and illness comprehensibility （β= 1. 489, P =0. 014） were significantly correlated to the global HRQOL. Conclusion Personal control, identity of symptoms and illness comprehensibility significantly influence the quality of live in the patients with early- and intermediate-stage HCC.