肝硬化是临床常见的慢性进行性疾病,也是慢性肝病发展的终末阶段。肠道菌群是目前研究的热点,肠道菌群的失调引起的各种因素的发生改变可能促进或加重肝硬化,引起肠源性内毒素血症,导致自发性腹膜炎、肝性脑病等并发症出现。中医药能够有效的改善肝硬化肠道菌群的失调,目前对调节肠道微生态治疗肝硬化的文献较少,缺乏系统性的总结,笔者就目前研究现状做单味中药、中药复方治疗肝硬化微生态进行综述。
Cirrhosis is a common chronic progressive disease, and also the end stage of the development of chronic liver disease. In- testinal flora is the hot spots of current study. The changes of various factors caused by intestinal flora imbalance may promote or aggravate cirrhosis, thus causing intestinal endotoxemia, leading to spontaneous peritonitis and hepatic encephalopathy and other concurrent diseases. Traditional Chinese medicine can effectively improve the intestinal flora imbalance of cirrhosis, but the current literature of intestinal micro- ecological treatment of cirrhosis is less and lack of systematic summary. The author makes a summary of the current intestinal microecologi- cal treatment of cirrhosis by studying single herb and compound treatment of traditional Chinese medicine.