中文摘要：

放疗是治疗恶性肿瘤的主要手段之一，但由于放疗抵抗现象的存在，放疗效果并不尽如人意。为缓解放疗抵抗，提高放疗效果，放疗增敏剂应运而生。RRx-001作为新近被发现的放疗增敏剂，表现出了良好的临床应用前景。本文就RRx-001的来源、安全性、放疗增敏活性及相关机制的研究进展进行综述。

英文摘要：

Radiotherapy is one of the most important methods to treat malignant tumors.Due to the presence ofradiation resistance,the effect of radiotherapy is not entirely satisfactory.To alleviate radiation resistance and improve theradiotherapy effect,radiosensitizers have emerged.As a newly discovered radiosensitizer,RRx-001has a good clinicalapplication prospect.This paper reviewed the research progress of RRx-001in source,safety,radiotherapy sensitizingactivity and related mechanisms.