目的探究老年冠心病病人不同中医证型与血脂水平间的关系。方法随机选取我院心血管内科拟诊为冠心病的老年病人167例,根据冠状动脉造影结果分为冠心病组(100例)及非冠心病组(67例),根据中医辨证分型分为痰阻心脉、心血瘀阻、阴寒凝滞、气虚血瘀四型,比较冠心病病人不同中医证型与血脂水平的关系。结果冠心病组总胆固醇(TC)、三酰甘油(TG)、低密度脂蛋白胆固醇(LDL-C)均高于非冠心病组,差异有统计学意义(P〈0.05);痰阻心脉证TC、LDL-C、载脂蛋白B均显著高于其他各证型,差异有统计学意义(P〈0.001);痰阻心脉证和心血瘀阻证TC显著高于其他证型,差异有统计学意义(P〈0.05)。结论老年冠心病中医证型以痰阻心脉证和心血瘀阻证常见,痰浊与血脂异常存在一定的相关性且痰阻心脉证中血脂最显著。
Objective To explore the relationship between traditional Chinese medicine(TCM)syndrome and serum lipid levels in elderly patients with coronary heart disease(CHD).Methods One hundred and sixty-seven elderly patients diagnosed as CHD were randomly selected from Department of Cardiology in our hospital,and divided into CHD group(n =100)and non-CHD group(n =67)according to the results of coronary angiography.Patients were divided into phlegm syndrome,blood stasis syndrome,chill stagnate syndrome,qi deficiency and blood stasis syndrome according to the syndrome differentiation of TCM.The serum lipid levels were observed in elderly patients with different TCM syndrome.Results The serum levels of total cholesterol(TC),triglyceride(TG)and low-density lipoprotein cholesterol(LDL-C)in CHD group were higher than that in non-CHD group(P〈0.05).The serum levels of TC,LDL-C,apolipoprotein B in patients with phlegm syndrome were higher than that in patients with other syndromes(P〈 0.001).The serum levels of TC in in patients with phlegm syndrome and blood stasis syndrome were higher than that in patients with other syndromes(P〈0.05).Conclusion The common TCM syndromes are phlegm syndrome and blood stasis syndrome.There is a certain correlation between phlegm syndrome and dyslipidemia.