中文摘要：

为探讨西医重度哮喘、中医虚哮型哮喘和维吾尔医异常黑胆质哮喘三者的交互关系,对156例支气管哮喘患者进行西医诊断分型,并按中医、维吾尔医的方法,进行辨证分型。分别采用：①用放射免疫分析法对白细胞介素-1（IL-1）、白细胞介素-6（IL-6）、肿瘤坏死因子α（TNF-α）、促肾上腺皮质激素（ACTH）、皮质醇（CS）和生长激素（GH）进行检测;②对促肾上腺皮质激素释放激素（CRH）,采用酶联免疫法（ELISA）进行检测;③用流式细胞仪对淋巴细胞凋亡,CD3,CD4,CD8,CD11b,CD18和CD62p进行检测。对测定结果使用SPSS12.0统计软件进行处理;计量资料用均数±标准差;多组均数比较用单因素方差分析进行描述;检验水准α=0.05。结果显示,对于年龄、病程,重度哮喘、虚哮型哮喘、异常黑胆质哮喘三者间的差异无统计学意义（P〉0.05）,三者症候症群重叠;淋巴细胞亚群及其介质CD4,CD8,CD4/CD8,CD11b和CD11b/CD18,在三种哮喘间无差异,无统计学意义（P〉0.05）;CD62p,TNF-α和淋巴细胞凋亡,差异有统计学意义（P〈0.05）;内源性皮质醇CS,ACTH,CRH在重度哮喘与异常黑胆质哮喘间有差异,有统计学意义（P〈0.05）,其他哮喘间无差异,无统计学意义。结论表明,重度哮喘、虚哮型哮喘和异常黑胆质哮喘,三者具有一定的交互性,表现是它们均病情严重,平均年龄大,三者症候症群重叠,且免疫及内分泌系统紊乱更为明显等。

英文摘要：

This paper studies the relationship between the severe asthma as is called in Western medicine, the virtual roar asthma in Chinese medicine, and the abnormal Savda asthma in Uygur medicine, 156 patients with bronchial asthma were diagnosed and classified, according to Western medicine, Chinese medicine, and Uygur medicine, respectively. The methods used include： （1） RIA analysis of interleukin-1 （IL-1）, interleukin 6 （IL-6） and tumor necrosis factor-α （TNF-α）, adrenocorticotropic hormone （ACTH）, cortisol （CS） and growth hormone （GH） detection; （2） the enzymelinked immunoassay （ELISA） in corticotropin-releasing hormone （CRH） test. （3） the flow cytometry on lymphocyte apoptosis, CD3, CD4, CD8, CD11b, CD18 and CD62p detection. The results were treated with SPSS12.0 statistical software; measurement data were expressed by mean ± standard deviation formula; multiple group means were compared with single-factor analysis of variance, tested with α= 0.05 level. Results show that severe asthma, asthma virtual roar, abnormal Savda asthma, with respect to age, duration, saw no significant difference （P〉0.05）, with the three symptom groups being overlapped; lymphocyte subsets and medium CD4, CD4, CD8,CD4/CD8,CD11b, CD11b/CD18 of them also saw no difference of statistical significance （P〉0.05）; but CD62p, TNF-α and lymphocyte apoptosis of them saw some difference of statistical significance （P〈0.05）; and CS endogenous cortisol, ACTH and CRH in severe asthma and abnormal Savda asthma were different with a statistical signi.ficance （P〈0.05）, with no differences of statistical significance for asthma. It is concluded that severe asthma, asthma virtual roar, abnormal Savda asthma are similar to some extent, with respect to severity in patient＇s conditions, seniority in average age, overlapping symptoms, and immune and endocrine system disorders.