从水朝阳旋覆花(Inula helianthus-aquatica)地上部分分离得到24个化合物,经波谱数据分析分别鉴定为aromaticin(1),8-epi-helenalin(2),bigelovin(3),2,3-dihydroaromaticin(4),carpesiolin(5),ergolide(6),inuchinenolidec(7),6α-acetoxy-isoinuviscolide(8),8-epi-inuviscollde(9),inuchinenolideB(10),tomentosin(11),1let,13-dihydrotomentosin(12),inuchinenolideA(13),4H-tomentosin(14),11β,13-dihydm-4H.tomentosin(15),11-epi-sundiversifolide(16),sundiversifolide(17),8,9,10-三羟基百里香酚(18),10-羟基-8,9-双氧亚异丙基百里香酚(19),8,10-二羟基-9-异丁酰百里香酚(20),8-羟基-9,10.二异丁酰百里香酚(21),8.羟基-9-异丁酰-10-(2.甲基丁酰)百里香酚(22),8,9-环氧-9,10-二异丁酰百里香酚(23)和8,9-环氧.3.异丁酰-10-(2.甲基丁酰)百里香酚(24)。除了化合物1-6外,其他化合物均为首次从该植物中分离得到。
Twenty-four compounds were isolated from the aerial parts of Inula helianthus-aquatica. On the basis of spec- tral data, their structures were identified as aromaticin ( 1 ), 8-epi-helenalin (2), bigelovin (3), 2,3-dihydroaromaticin (4) ,carpesiolin (5), ergolide ( 6 ), inuchinenolide C ( 7 ), 6ct-acetoxy-isoinuviscolide ( 8 ), 8-epi-inuviscolide ( 9 ), inuchinenolide B ( 10 ), tomentosin ( 11 ), 11 ct, 13-dihydrotomentosin ( 12 ), inuchinenolide A ( 13 ), 4H-tomentosin (14), 11β, 13-dihydre-4H-tomentosin ( 15), 11-epi-sundiversifolide ( 16), sundiversifolide ( 17), 8,9,10-trihydroxythy- tool ( 18 ), 10-hydroxy-8,9-dioxyisopropylidenethymol ( 19 ), 8,10-dihydroxy-9-isobutyryloxythymol ( 20 ), 8-hydroxy-9, 10-diisobutyryloxythymol ( 21 ), 8-hydroxy-9-isobutyryloxy-10-(2-methylbutanoyl) thymol ( 22 ), 8,9-epoxy-3, 10-di- isobutyryloxythymol (23), and 8,9-epoxy-3-isobutyryloxy-10- (2-methylbutanoyl) thymol ( 24 ). All the compounds ex- cept 1-6 were isolated from this plant for the first time.