中文摘要：

背景：乙型肝炎病毒（HBV）感染伴发抑郁症是一种常见的现象。建立精确并且有时效的工具,用以评估HBV患者抑郁症状,对研究和临床实践是非常重要的。目的：这项研究测试了抑郁症状快速评定量表自评版（QIDS-SR）在乙型肝炎患者中使用的心理测量学特性。方法：这项研究招募了245名患有乙型肝炎病毒和相关肝病的抑郁症患者。采用蒙特玛莉抑郁评定量表（MADRS）和QIDS-SR评估抑郁症状的严重程度。结果：QIDS-SR的内部一致性（（Cronbachα）为0.796.其总分与MADRS总分显著相关r=0.698,p〈0.001）。探索性因素分析的QIDS-SR显示一维测量性能结论：QIDS-SR（中文版）在乙型肝炎患者中有良好的心理测量学特性,并且在评估临床抑郁症方面是有用的。

英文摘要：

Background： Comorbid depression in Hepatitis B virus（HBV） is common. Developing accurate and timeefficient tools to measure depressive symptoms in HBV is important for research and clinical practice in China. Aims： This study tested the psychometric properties of the Chinese version of the 16-item Quick Inventory of Depressive Symptomatology（QIDS-SR） in HBV patients. Methods： The study recruited 245 depressed patients with HBV and related liver disease. The severity of depressive symptoms was assessed with the Montgomery-Asberg Depression Rating Scale（MADRS） and the QIDS-SR. Results： Internal consistency（Cronbach＇s alpha） was 0.796 for QIDS-SR. The QIDS-SR total score was significantly correlated with the MADRS total score（r=0.698, p0.001）. The QIDS-SR showed unidimensional measurement properties in exploratory factor analysis. Conclusions： The QIDS-SR（Chinese version） has good psychometric properties in HBV patients and appears to be useful in assessing depression in clinical settings.