贵金属团簇(noble metal clusters)是近年来新兴的一类荧光标记材料.由于具有物理尺寸小、荧光可调及生物相容性等优异的性能使得其在生物成像及检测领域都有着广泛的应用前景.本文讨论了贵金属团簇的制备和荧光特性,重点论述了其作为标记材料在细胞成像方面及体外检测应用中的研究进展.
The noble metal clusters is a new class of fluorescent material. With a set of attractive features, such as ultrasmall size, fluorescence tenability and good biocompatibility, the clusters are ideal candidate for the fluorescent labels and detection. In this review, we summarize the synthesis and fluorescence characteristic of the clusters, and the recent development of their application in bioimging and in vitro detection.