中文摘要：

目的：明确不同孕期妊娠梅毒患者的治疗对妊娠结局的影响。方法：共124例妊娠梅毒妇女接受了驱梅治疗,包括孕早期42例,孕中期40例,孕晚期42例。结果：124例妊娠梅毒患者中不良妊娠33例,包括流产死产14例,先天性梅毒患儿19例。孕早期不良妊娠率为7.14%,孕中期为22.5%,孕晚期为50%,三组比较差异有统计学意义（P〈0.05）。结论：妊娠梅毒患者治疗越早,不良妊娠发生率越低。

英文摘要：

Objective：To determine the influence of the treatment of pregnant syphilis on the outcome of in different gestation. Methods：One hundred and twenty-four pregnant women with syphilis were treated, with penicillin including 42 women in the first trimester, 40 in the second trimester and 42 in the third trimester. Results：Adverse pregnant outcomes occurred in 33 pregnancies （ miscarriage and stillbirth in 14 women and congenital syphilis in 19 women） . The incidence of adverse pregnant outcomes was 7.14% in the first trimes-ter, 22.5% in the second trimester and 50% in the third trimester. The differences among the three groups were significant （P〈0.05）. Conclusion： The earlier treatment for the pregnancy with syphilis begins, the lower the incidence of adverse pregnancy outcomes will be.