目的 了解民营企业家胰岛素抵抗的患病情况.方法 人群分为民营企业家组和职工组,检测血压、身高、体重、血糖、血胰岛素、总胆固醇、甘油三酯、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇、血尿酸、C反应蛋白及肝肾功能.结果 与职工组比较,民营企业家组体质量指数、血糖、血胰岛素、总胆固醇较高,差异有统计学意义(P<0.01);收缩压、血胰岛素与血糖比值、胰岛素抵抗指数、甘油三酯、低密度脂蛋白胆固醇、C反应蛋白增高,差异有统计学意义(P<0.05);但舒张压、高密度脂蛋白胆固醇、血尿酸、尿素氮、血肌酐差异无统计学意义(P>0.05).结论 民营企业家较职工更容易出现值得关注的胰岛素抵抗倾向,应及早采取预防措施.
Objectives To investigate the condition of insulin resistance in local enterpriser people. Methods The blood pressure, body height, weight, blood glucose (BG), insulin (INS), total cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C), low density lipoprotein-cholesterol (LDL-C), uric acid (UA), C-reactive protein (CRP), hepatic and renal function were detected in the local enterpriser group and control (workers) group, respectively. INS/BG and HOMA-IR were calculated. Results Comparing two groups: There were significantly statistical deference in BMI, BG, INS, TG (P〈0.01), SBP, NS/BG, HOMA-IR, TG, LDL-C, CRP (P〈 0.05), but there were no significantly statistical deference in DBP, HDC-C, UA, BUN, Cr (P 〉 0.05). Conclusions The insulin resistance is quite often to see in the local enterpriser people, we must pay more attention to these people for prevention of cardiovascular diseases.