中文摘要：

叙述了一系列增强纳米粒子光热性能的方法,包括通过自组装方法调控纳米粒子的空间排列,进而优化电子结构和光热转化性能;在纳米粒子及其组装结构外表面进一步包覆具有光热性质的聚合物等.这些手段能够有效地增强光热试剂在近红外光区的消光能力,达到增强光热性能的目的.另外,包覆聚合物壳层后,纳米粒子的胶体稳定性、光稳定性以及生物兼容性都能得到进一步提高,为后续的体外细胞实验和动物体内肿瘤模型实验提供了可能.

英文摘要：

Nanoparticles （NPs） that are capable to convert near-infrared （NIR） irradiation into thermal energy have been demonstrated as the robust media for tumour curing. In this scenario, the photothermal performance of NPs greatly depends on their size, morphology, surface property, as well as the self-assembly architectures. Therefore,the practical applications of photothermal NPs in cancer therapy are determined by the technique progresses of nano-fabrications and multi-functional integration. In this scenario, the photothermal performance of NPs greatly depends on their size, morphology, surface property, as well as the self-assembly architectures. Therefore,the practical applications of photothermal NPs in cancer therapy are determined by the technique progresses of nano-fabrications and multi-functional integration. In this article,we summary a series of methods to enhance NP photothermal performance, such as control preparation of nanostructures, directing NPs self-assembly into specific architectures, and further photothermal polymer coating. The combination of these issues ensures the improvement of photothermal performance,colloidal and physiological stability, as well as biocompatibility.