在不同种类的男繁殖的道被 carboxylesterases 的男性依赖者的 overexpression 的类似的模式描绘。这现象为精子发生,精子成熟,和精子使用显示这些酶的男联系性的功能。最近, epididymis 特定的基因说出 Ces7 的一篇小说被克隆并且描绘,它属于 carboxylesterase 家庭。在精子成熟和存储学习 CES7 的函数, CES7 recombinant 蛋白质在 baculovirus 被表示系统。recombinant 蛋白质有 carboxylesterase 活动 hydrolyzing 胆固醇酉旨和胆碱酉旨。carboxylesterase 可能在男繁殖的道涉及酉旨水解作用,精子成熟,和存储的 CES7。
The male reproductive tracts in different species are characterized by similar patterns of male-dependent overexpression of carboxylesterases. This phenomenon indicates male sex-associated functions of these enzymes for spermatogenesis, sperm maturation, and sperm use. Recently, a novel epididymis-specific gene named Ces7 was cloned and characterized, which belongs to the carboxylesterase family. To study the functions of CES7 in sperm maturation and storage, CES7 recombinant protein was expressed in baculovirus system. The recombinant protein had carboxylesterase activity hydrolyzing cholesterol ester and choline ester. CES7 as carboxylesterase might be involved in ester hydrolysis, sperm maturation, and storage in male reproductive tract.