通过自由基聚合方法合成聚丙烯酰胺(PAAM)水凝胶、丙烯酰胺(AAM)与甲基丙烯酸(MAA)的不同摩尔比的P(AAM-co-MAA)水凝胶,并对这些水凝胶的形貌和膨胀性能及pH敏感性能进行研究。结果表明,相比PAAM水凝胶,P(AAM-co-MAA)水凝胶的膨胀性能提高,但当AAM与MAA摩尔比为13∶2时,P(AAM-co-MAA)水凝胶具有更好的膨胀性和pH敏感性。这些水凝胶的特殊性能使它们有望应用于药物的缓控释放方面。
The PAAM hydroges, P(AAM-co-MAA) hydrogels of different MAA and MAA, hydrogel were perapared by free radical polymerization methods. The morphology characterization, swelling ability and pH-sensitivity of these hydrogels were studied. The results showed that the(AAM-co-MAA) hydrogel exhibited better swelling capability and pH sensitivity than that of the PAAM. The(AAM-co-MAA) hydrogel with reasonable ratio(AAM∶MAA=13∶2) had best swelling capability and pH sensitivity. The hydrogel with these special properties was expected to be applied to the field of drug controlled release.