利用接枝的方法制备了4种纳米RE2O3/硫酸酯化壳聚糖杂化材料(Nd2O3-TDI-CS,Eu2O3-TDI-CS,La2O3-TDI-CS,Sc2O3-TDI-CS,TDI=甲苯二异氰酸酯,CS=壳聚糖),用红外光谱、热重分析和扫描电镜表征了产物,结果表明壳聚糖接枝于经过活化后的纳米氧化物表面.抗凝血实验结果和复钙实验结果说明制备的4种杂化材料比纳米稀土氧化物具有更好的抗凝血性能.
Four hybrid materials of RE2O3-TDI-CS(TDI=toluene 2,4-diisocyanate,CS=chitosan,RE= Nd,Eu,La,Sc) were prepared by the method of graft.The materials were characterized by infrared spec-troscopy,thermogravimetric and scanning electron microscopy,and results showed that the CS was grafted on the surface of rare earth nano-oxides which was modified by TDI.The results of the experiment of anti-coagulant and recalcification time showed that the materials have better anticoagulant action than that of RE2O3.