中文摘要：

大孔吸附树脂因其结构易于调控、吸附选择性高、可再生使用等诸多优点，在天然植物有效成分的提取分离中发挥了重要作用。本文介绍了近年来在高选择性吸附树脂结构设计方面的研究进展，主要分为两个方面：（1）基于多重弱相互作用的协同效应设计树脂骨架结构，针对吸附质分子结构特点，在树脂骨架上引入能发生氢键、静电、偶极作用的特殊功能基团，并有目的地调控树脂的疏水骨架，可用于天然植物中每一类有效成分的高纯度提取，甚至每一类有效成分的单体组分的分离；（2）树脂孔结构的调控，主要集中在改变传统的非良溶剂致孔的方法，利用聚付氏烷基化反应在树脂初始聚苯乙烯结构之间引入亚甲基刚性交联桥，得到孔径均匀的吸附树脂，使得此类树脂兼具了吸附和筛分的双重功能。

英文摘要：

The macroporous polymeric adsorbents have been widely applied in separation and purification of natural products due to its structure is easy to control, adsorption selectivity is high, and its use is renewable. In this article, the several research progresses for synthesis and application of the polymeric adsorbent was reviewed, mainly divided into two aspects： （1） Structure of the polymeric adsorbent matrix was designed base on the synergistic effect of multiple weak interactions, such as hydrogen bonding interaction, electrostatic interaction, dipolar interaction, and so on. Meanwhile, the hydrophobic skeleton of the adsorbent was also controlled purposely according to the structure characteristic of the adsorbates. This adsorbent can be used to prepare the high purity extract of the special active component in natural product, even to separate the monomer components in one kind of effective principle. （2） Controlling of the pore structure of the adsorbent mainly focus on the pore formed method. In order to get the narrow distribution of the pore diameter of the adsorbent, the traditional non-solvating pore formed method was changed to post crosslink of methylene between the initial structures of the polystyrene adsorbent based on the Friedel-Craft Alkylation reaction. As the result, this kind of adsorbent should exhibit the double function of adsorption and sieving effect.