中文摘要：

随着肿瘤干细胞学说的不断发展,肿瘤干细胞标志物逐渐成为肿瘤研究的热点.CD44作为最常用的肿瘤干细胞标志物,近年来更是被广泛涉及.本文就以往关于CD44的研究成果,重点介绍CD44调控肿瘤发生发展机制研究的新进展.

英文摘要：

With the continuous development of the cancer stem cell theory,biomarkers for CSCs （Cancer stem cells） have gradually become the hot issues in tumor research.As the most commonly used CSCs biomarker,CD44 gains lots of attentions.This paper will review recent research about CD44 molecule and its powerful role in regulating tumor progenesis and progression.