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拥有“飞行时间”技术的PET/CT性能分析
  • ISSN号:1672-8270
  • 期刊名称:中国医学装备
  • 时间:2012
  • 页码:1-5
  • 分类:TH774[机械工程—仪器科学与技术;机械工程—精密仪器及机械]
  • 作者机构:[1]北京大学肿瘤学院暨北京市肿瘤防治研究所核医学科,恶性肿瘤发病机制及转化研究教育部重点实验室北京100036
  • 相关基金:国家自然科学基金(81071198)“肿瘤靶向纳米探针NIRF-CCPM-RGD的多功能分子影像研究”
  • 相关项目:肿瘤靶向纳米探针NIRF-CCPM-RGD的多功能分子显像研究
中文摘要:

目的:研究并分析拥有飞行时间(TOF)技术的PET/CT相关性能。方法:参照美国国家电气制造协会(NEMA)NU2—2007标准和厂家测试手册,对PET/CT的能量与时间分辨率、空间分辨率、灵敏度、散射分数、计数特性和图像质量进行性能测试和分析,并对不同型号仪器的性能进行比较,初步探讨飞行时间(TOF)技术对设备性能的影响。结果:系统的能量分辨率和时间分辨率分别为11.59%和499.3ps;空间分辨率在1cm处为4.54mm(横向)和4.85mm(轴向),10cm处为5.13mm(横向径向)、5.55mm(横向切线)和5.76mm(轴向);中心和偏离中心10cm处的灵敏度分别为6.4和6.8(c!os/kBq);散射分数为32%;等效噪声计数率(NECR)在14.03kBq/ml时达到峰值为97.6kcps;模体图像中可以清楚分辨直径为10mm的最小热球。结论:拥有飞行时间技术的PET/CT各项性能指标都很优越,尤其在于图像质量的提高,可以缩短采集时间和减少注射药物剂量。

英文摘要:

Objective: The performances of a PET/CT scanner with time-of-flight (TOF) capability were measured and studied. Methods: Performances measurements on the scanner were made using the National Electrical Manufactures Association (NEMA) NU2- 2007 procedures and Company's Performance Test Manual. The energy/timing resolution, spatial resolution, sensitivity, the scatter fraction, counts performance and imaging quality were measured and analyzed. Different types of PET/CT were compared and the imagingcapabilities of TOF were discussed. Results: The system and 499.3 ps. The transverse and axial resolutions near energy and timing resolution were measured to be 11.59% the center were 4.54mm and 4.85mm, whereas at 10 cm were 5.13 mm, 5.55 mm, 5.76 mm. The absolute sensitivity of this scanner was 6.4(center) and 6.8(10 cm) cps/ kBq, whereas scatter fraction was 32%. The peak NECR was 97.6kcps and occured at 14.03kBq/mL. Image quality measurements with phantom showed that the 10 mm diameter lesion could be clearly distinguished. Conclusion: The PET/CT which achieved TOF capability performed good characteristic, especially in the improvement of image quality. And shorter scan times and lower dose could be gained at the same image quality.

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期刊信息
  • 《中国医学装备》
  • 中国科技核心期刊
  • 主管单位:中华人民共和国卫生部
  • 主办单位:中国医学装备协会
  • 主编:崔泽实
  • 地址:北京市西城区南纬路27号305-307室
  • 邮编:100050
  • 邮箱:
  • 电话:010-63028803 63029869
  • 国际标准刊号:ISSN:1672-8270
  • 国内统一刊号:ISSN:11-5211/TH
  • 邮发代号:80-373
  • 获奖情况:
  • 国内外数据库收录:
  • 被引量:10509