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改良电休克治疗对抑郁症患者延迟回忆能力的影响及相关因素分析
  • ISSN号:1000-0399
  • 期刊名称:安徽医学
  • 时间:2014.4.30
  • 页码:411-413
  • 分类:R473.74[医药卫生—护理学;医药卫生—临床医学]
  • 作者机构:[1] 安徽省精神卫生中心精神科 ,合肥230032, [2] 安徽医科大学第一附属医院神经内科 ,合肥230022
  • 相关基金:国家自然科学基金(81100806)
  • 相关项目:基于脑功能连接的忽视症神经机制及rTMS干预的研究
中文摘要:

目的:探索改良电休克治疗( modified electraconvulsive therapy ,MECT)前后抑郁症患者延迟记忆能力变化情况及影响因素。方法对11例抑郁症患者分别在治疗前、治疗后48小时内进行测验,以中文听觉词汇学习测试( Chinese auditory learning test,CAVLT)分钟延迟回忆分数为终点指标,同时评定治疗前后患者汉密尔顿抑郁量表( Hamilton depressive scale ,HAMD)分值。结果 MECT治疗后患者延迟回忆分数降低,差异有统计学意义(t=4.190,P=0.002);MECT治疗后患者HAMD分值降低,差异有统计学意义( t=15.493,P<0.001);延迟回忆能力改变值与治疗前延迟回忆分数相关( r=0.801,P=0.003)。结论 MECT治疗降低抑郁症患者延迟回忆能力,延迟回忆能力损害程度与治疗前延迟回忆能力有关。

英文摘要:

Objective To explore the change of delayed memory in patients with depression before and after the modified electrocon -vulsive therapy ( MECT ) .Methods Eleven patients with depression were tested with Chinese auditory learning test before the treatment and within 48 hours after treatment ,while Hamilton Depressive Scale ( HAMD) was also assessed .Results After treatment of MECT ,the delayed recall scores of patients were significantly decreased (t =4.190,P=0.002);HAMD scores were also significantly decreased (t=15.493, P<0.001 );the change of delayed recall scores were significantly associated with the value of pre -treatment delayed recall scores ( r=0.801,P=0.003).Conclusion MECT impairs the ability of delayed recall in depression patients , and the damage degree of delay recall after MECT is correlated to the ability of pre-treatment delayed recall .

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期刊信息
  • 《安徽医学》
  • 中国科技核心期刊
  • 主管单位:安徽省卫生厅
  • 主办单位:安徽省卫生厅
  • 主编:周可能
  • 地址:合肥市永红路15号
  • 邮编:230061
  • 邮箱:ahyxzz@163.com
  • 电话:0551-62827688
  • 国际标准刊号:ISSN:1000-0399
  • 国内统一刊号:ISSN:34-1077/R
  • 邮发代号:26-22
  • 获奖情况:
  • 国内外数据库收录:
  • 被引量:23400