探索微粒的效果的目的有关系在心 repolarization/depolarization 和心率可变性(HRV ) 上的空气动力学的直径(PM2.5 ) 的不到 2.5 m。我们进行了一块面板的方法从 2007 ~ 2008 在北京与心疾病为老题目学习。当 42 个题目的心电图(ECG ) 索引也反复被记录时, PM2.5 每天连续地为 20 h 在一个固定车站被测量。气象学的数据从分享服务系统的中国气象学的数据被获得。一个混合线性回归模型被用来估计在 PM2.5 和 ECG 索引之间的协会。模型好久被调整,身体团索引,性,这个星期和气象学的白天。结果反映 HRV 的 ECG 索引上的 PM2.5 的重要不利效果统计上被观察, HRV 上的 PM2.5 的最强壮的效果在上落后在我们的学习的 1 天。然而,在 PM2.5 和 ECG 索引思考心 repolarization/depolarization 之间没有协会。另外,没有高血压,有高血压的题目上的 PM2.5 的效果比在这些题目上大。这研究看了周围的 PM2.5 的结论能与心疾病影响老人的心脏的自治功能,并且有高血压的题目看起来对 PM2.5 导致的自治机能障碍更易感。
Objective To explore the effects of particulate matters less than 2.5 μm in aerodynamic diameter (PM2.5) on heart repolarization/depolarization and heart rate variability (HRV). Methods We conducted a panel study for elderly subjects with heart disease in Beijing from 2007 to 2008. PM2.5 was measured at a fixed station for 20 h continuously each day while electrocardiogram (ECG) indexes of 42 subjects were also recorded repeatedly. Meteorological data was obtained from the China Meteorological Data Sharing Service System. A mixed linear regression model was used to estimate the associations between PMz.s and the ECG indexes. The model was adjusted for age, body mass index, sex, day of the week and meteorology. Results Significant adverse effects of PM2.5 on ECG indexes reflecting HRV were observed statistically and the strongest effect of PM2.s on HRV was on lag i day in our study. However, there were no associations between PM2.5 and ECG indexes reflecting heart repolarization/depolarization. Additionally, the effects of PM2.5 on subjects with hypertension were larger than on the subjects without hypertension. Conclusion This study showed ambient PM2.5could affect cardiac autonomic function of the elderly people with heart disease, and subjects with hypertension appeared to be more susceptive to the autonomic dysfunction induced by PM2.5.