中文摘要：

肺的药和基因交货系统与最小的药损失，精确量子化，高本地的药集中和低副作用的优点在肺疾病的处理成为了一条吸引人的途径。然而，特殊注意应该对肺的生物障碍被给予。交货系统需要小心地被设计以便克服这些生物障碍并且最大化药和基因免职到肺。肺的药和基因交货系统能提供为把药和基因送到肺鼓励结果的一些。明确地，一些基于类脂化合物、基于聚合物的交货系统能与最小或可以忽略的毒性控制并且支撑药和基因的版本。这评论为各种各样的肺疾病的处理集中于药和基因的肺的交货的最近的发展。对肺，交货设备，管理的线路和为药和基因的交货系统的障碍肺的交货被描述。基于临床的要求的快速的开发，用为肺的交货药和基因的交货系统的新奇途径需要被构造，它被相信以后在肺疾病的治疗起一个重要作用。

英文摘要：

Pulmonary drugs and genes delivery systems have become an attractive approach in the treatment of lung diseases with the advantages of minimal drug loss,precise quantization,high local drugs concentration and low side effects.However,special attention should be paid to the biological barriers of the lung.The delivery systems need to be designed carefully in order to overcome these biological barriers and maximize the drugs and genes deposition to the lungs.Pulmonary drugs and genes delivery systems can offer some encouraging results for delivering drugs and genes to the lungs.Specifically,some lipid-based and polymer-based delivery systems could control and sustain the release of drugs and genes with minimal or negligible toxicity.This review focuses on the latest development of pulmonary delivery of drugs and genes for the treatment of various lung diseases.The barriers to the lung,the delivery devices,the route of the administration and the delivery systems for drugs and genes pulmonary delivery are described.Based on the rapid development of clinical requirement,novel approaches using delivery systems for pulmonary delivery drugs and genes need to be constructed,which is believed to play an important role in the therapy of lung diseases in the future.