中文摘要：

以NC-510为先导化合物，设计合成了一系列基于噻（二）唑的丙烯腈类化合物，其结构经。HNMR和MS等谱图表征确证。杀虫活性测试结果表明，在500mg／L剂量下，所合成的化合物对同翅目害虫蚜虫均具有100％杀虫活性；进一步研究发现，化合物7a对蚜虫杀虫活性（LC50=3．46mg／L）与先导化合物NC-510的活性（LC50=0．61mg／L）接近，具有进一步优化前景。

英文摘要：

A series of novel acrylonitrile compounds containing thia（dia）zole group were designed and synthesized using NC-510 as the lead compound, and their structures were characterized by 1H NMR and MS. The results of bioassay indicated that the title compounds exhibited 100% mortalit against Aphis fabae at 500 mg/L. In particular, the compound 7a displayed the best activity, the value of LC50 was as low as 3.46 mg/L and its insecticidal potency was close to NC-510 （LC50=0.61 mg/L）, so it had a further optimization prospect.