目前临床上能够有效且快速转复心房颤动(简称房颤)、心房扑动(简称房扑)的药物还比较少,伊布利特(ibutilide)转复房颤、房扑具有起效快,成功率高,安全性好的特点,其治疗心律失常的基本作用原理为延长动作电位时程和有效不应期来终止折返激动。伊布利特与普罗帕酮、胺碘酮、电复律、镁剂联用可提高临床疗效。
ctive and rapid of drugs of cardioversion of atrial fibrillation and atrial flutter are rare at present. Ibutilide is characterized by rapid effect in cardioversion of atrial fibrillation/atrial flutter, high converting rate and reliable security. The basic mechanism of treaEffeting arrhythmia is prolonging action potential duration and effective refractory period to terminate excitable reentry. Combined with propafenone, amiodarone, internal atrial cardioversion or magnesium could raise the clinical effects.