目的探讨颅内外血管重建术治疗烟雾病的临床疗效和治疗经验。方法收集2011年3月至2012年12月济宁医学院附属医院神经外科收治的28例烟雾病患者,其中缺血型22例,出血型6例,所有患者均接受颅内外血管重建术的治疗。结果23例患者术后临床症状消失,3例患者术后临床症状好转,2例患者因并发脑梗死术后神经功能较术前恶化。结论颅内外血管重建术为烟雾病患者重新建立颅内血运,可降低患者再次发生脑梗死和脑出血的概率,临床效果满意,是治疗烟雾病的有效方法。
Objective To explore the clinical efficacy and experiences of extracranial-intracranial revascularizatiou for the treatment of Moyamoya disease. Methods Clinical data of 28 patients with Moyamoya disease were analyzed retrospectively form March 2011 to December 2012, including 22 cases of ischemic lesion, 6 case of hemorrhage lesion, all patients received extracranial-intracranial revascularization treatment. Results 23 patients had excellent recovery after surgery, the incidence of transient ischemic attack and cerebral hemorrhage were obviously reduced; the clinical symptoms were improved in 3 patients; the neurologic function of 2 patients deteriorated because of the cerebral infarction. Conclusions Extraeranial-intracranial revascularization can re-establish the blood circulation for Moyamoya disease patients, reduce the recurrence of cerebral infarction and cerebral hemorrhage. Extracranial- intracranial revaseularization is an effective treatment for Moyamoya disease.