目的探讨中心性渗出性脉络膜视网膜病变(CEC)的病因。方法对临床确诊为CEC的32例患者进行病史调查、行高稀释度结核菌素纯蛋白衍生物(PPD)试验,胸部X线片检查,外周血常规、C-反应蛋白、血红细胞沉降率检查,弓形体(T)、其他(O)、风疹病毒(R)、巨细胞病毒(C)、单纯疱疹病毒(H)检测(TORCH检测),梅毒检测等,明确可能的病因。结果32例患者中均无结核病史,胸部X线片检查均无全身活动性结核的证据,PPD试验阳性率37.5%。对PPD阳性患者经抗结核治疗病情稳定或好转。TORCH检测IgM抗体均阴性。梅毒初筛试验均阴性。结论未发现与CEC直接相关的感染因素,CEC脉络膜新生血管为特发性的可能性较大。
Objective To analyze the etiology of central exudative chorioretinopathy(CEC). Methods A total of 32 CEC patients were asked the medical history, and underwent examination of purified protein derivative(PPD)test, chest X-ray, blood routine test, C-reactive protein, erythrocyte sedimentation rate, TORCH test and rapid plasma regain cirde card test, to determine the possible causes of CEC. Results Thirty two patients didn't have the history of tuberculosis, and no evidence of systemic active tuberculosis was found in the chest X-ray examination, the results of PPD test showed the positive rate was 37.5 %. The disease condition of paitents with positive result of PPD test was stable or was alleviated after antituberculosis therapy. All the results in IgM of TORCH test and rapid plasma regain cirde card test were negative. Conclusion No infectious factors related to CEC was found, thus choroidal neovascularization of CEC might be idiopathic.