随着生活水平的日益提高,由代谢紊乱引起的肥胖、糖尿病和脂肪肝等代谢性疾病成为继癌症后困扰人们的又一大难题,而AMPK作为代谢调控的核心因子成为人们研究的重点和热门领域.对AMPK调控机制的研究为代谢性疾病的治疗与预防提供了新的思路.
With the improvement of the living standard, meta- bolic diseases, such as obesity, diabetes and fatty liver disease, become major issuesfor people. As the key regulatory factor of metabolic pathways, the protein ki- nase AMPK has attracted broad attention. The research on the mechanism of AMPK activation can provide new insights into prevention and treatment of the metabolic diseases.