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慢性腰痛对脊旁多裂肌萎缩影响的临床研究
  • ISSN号:1003-0034
  • 期刊名称:《中国骨伤》
  • 时间:0
  • 分类:R681.55[医药卫生—骨科学;医药卫生—临床医学;医药卫生—外科学]
  • 作者机构:[1]宁波市鄞州第二医院骨科,浙江宁波315000, [2]浙江大学医学院附属邵逸夫医院骨科,浙江大学邵逸夫临床医学研究所,浙江杭州310016
  • 相关基金:基金项目:国家自然科学基金(编号:81301585、81171739、81101378、81271971、81271972、31270997);浙江省自然科学基金(编号:Y2110372、LQ13H060001);浙江省医药卫生科研项目(编号:201336877)
中文摘要:

目的:明确慢性腰痛对脊旁多裂肌净横截面积大小及脂肪化程度的影响。方法:2010年3月至2013年8月对门诊治疗的腰痛患者进行回顾性分析,最终筛选出31例符合非特异性慢性腰痛患者,其中男19例,女12例;年龄23~55岁,平均36.4岁。主要症状是反复腰痛,病程大于1年,X线、CT、MRI均未见明显异常。采用MRI成像测量同一病例先后不同时间点多裂肌净横截面积及T2信号比率的变化,再获取2次MRI检查时VAS和Oswestry功能障碍评分,分析先后2次测量多裂肌净面积及T2信号比率的变化与腰痛的病程、VAS、Oswestry功能障碍评分的相关性,从而得出腰痛对脊旁多裂肌的影响。结果:同一病例第2次MRI检查多裂肌净横截面积明显小于第1次MRI检查,T2信号比率则明显高于第1次MRI检查(P<0.05)。多裂肌净横截面积减小率与VAS评分、病程和Oswestry功能障碍评分均呈正相关(P<0.001),而T2信号比率增加率与VAS评分、病程和Oswestry功能障碍评分均无相关性(P>0.05)。结论:慢性腰痛是脊旁多裂肌萎缩和脂肪化的重要原因,腰痛时间、程度和功能障碍程度均与多裂肌萎缩呈正相关。

英文摘要:

Objective:To identify the affect of chronic low back pain on multifidus muscle atrophy and fatty infiltration. Methods:From March 2010 to August 2013,a retrospective study were carried out in the department of orthopedics of patients with low back pain. Finally 31 cases were selected to this study including 19 males and 12 females with an average age of 36.4 years ranging from 23 to 55 years. The main symptoms of these patients were repeated back pain. Duration was more than 1 year. X ray,CT,MRI showed no obvious abnormalities. The changes of net cross sectional area of multifidus and T2 signal ratio of the same patient were measured at different time by MRI. VAS and Oswestry disability scores were recorded in two MRI ex-amination. Correlation between these change of multifidus net area and T2 signal ratio in two times measurement and duration of low back pain,VAS,Oswestry disability scores were analyzed to find the affection of low back pain on paraspinal multifidus muscle. Results:The net multifidus cross sectional area in same case by the second follow up MRI is significantly smaller than that of the first follow up,T2 signal ratio at second was significantly higher than that of the first (P〈0.05). The net cross sec-tional area of multifidus muscles reduced rate were positively correlated with VAS scores ,duration and of Oswestry disabilitry scores (P〈0.001). The rate of increase in T2 signal ratio was not correlated with VAS scores ,duration and the Oswestry dis-ability scores (P>0.05). Conclusion:Chronic low back pain is one of the most important reasons of paraspinal multifidus mus-cle atrophy and fatty. The duration,VAS and Oswestry disability scores of chronic low back pain were positively correlated with the multifidus muscle atrophy.

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期刊信息
  • 《中国骨伤》
  • 中国科技核心期刊
  • 主管单位:国家中医药管理局
  • 主办单位:中国中西医结合学会 中国中医科学院
  • 主编:董福慧
  • 地址:北京市东直门内南小街甲16号
  • 邮编:100700
  • 邮箱:zggszz@sina.com
  • 电话:010-64089487
  • 国际标准刊号:ISSN:1003-0034
  • 国内统一刊号:ISSN:11-2483/R
  • 邮发代号:82-393
  • 获奖情况:
  • 1999年首届国家期刊奖提名奖,第二届全国中医药优秀期刊二等奖
  • 国内外数据库收录:
  • 美国化学文摘(网络版),波兰哥白尼索引,荷兰文摘与引文数据库,美国生物医学检索系统,中国中国科技核心期刊
  • 被引量:27553