目的探讨氟尿嘧啶类化疗药物外周静脉应用外渗后局部组织损伤处理的护理效果。方法对65例癌症化疗患者应用氟尿嘧啶类药物外渗300例次进行随机分为观察组和对照组各150例次,观察组采用利多卡因加氟美松对外渗局部持续湿敷12~24h并间断冷敷12~24h,对照组采用利多卡因加氟美松局部封闭后加间断冷敷12~24h。结果观察组局部肿胀消退时间明显优于对照组,差异有统计学意义,P〈0.01;观察组和对照组皮下出血情况比较,差异有统计学意义,P〈0.05;观察组皮下淤血恢复时间短于对照组,P〈0.01。结论氟尿嘧啶类药物外周静脉应用,外渗后采用利多卡因加氟美松持续湿敷加间断冷敷,局部肿胀消退快,痛苦少,患者乐于接受,避免了局部封闭给患者带来的痛苦及损伤。
Objective To explore the nursing efficacy of handling methods for local tissue damage induced by venous fluorouraeil exosmosis. Methods 64 cancer patients who were used fiuorouracil had 300 venous exosmosis eases,these were divided into two groups randomly with 150 eases in each group.In the experimental group, lidocaine plus dexamethasone acetate were used for wet compress for 12-24 hours continuously, then cold dressing for 12-24 hours discontinuously.In the control group, lidoeaine plus dexamethasone acetate were used for local block,then cold dressing for 12-24 hours discontinuously. Results The time of local swelling reduction was shorter(P 〈 0.01 ), the condition of subcutaneous hemorrhage was lighter(P 〈 0.05), the recovery time of subcutaneous stasis of blood was shorter (P 〈 0.01 ) in the experimental group than that in the control group. Conclusions It can reduce patients' pain and local swelling by using lidocaine plus dexamethasone acetate for continuouswet compress plus discontinuous cold dressing to treat venous fluorouracil exosmosis.Patients were willing to accept it and it can avoid the pain and damage induced by local block.