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  • ISSN号:1671-4733
  • 期刊名称:《淮南职业技术学院学报》
  • 时间:0
  • 分类:R749.13[医药卫生—神经病学与精神病学;医药卫生—临床医学]
  • 作者机构:[1]上海第七人民医院,上海201203
  • 相关基金:上海市医学重点专科资助项目(ZK2012A25);上海市浦东新区中医特色专科项目(PDZYXK-1-2014001)
中文摘要:

目的:观察醒神解郁汤联合盐酸舍曲林治疗脑卒中后轻度抑郁的临床疗效。方法:将60例脑卒中后抑郁患者随机分为2组,各30例。对照组给予盐酸舍曲林口服;观察组在对照组治疗基础上给予醒神解郁汤治疗。2组疗程均为6周。观察2组临床疗效,治疗前后汉密尔顿抑郁量表(HAMD)评分。结果:总有效率治疗组86.70%,对照组70.00%,2组比较,差异有统计学意义(P〈0.05)。治疗后组患者HAMD评分均显著低于同组治疗前,与治疗前比较,差异有统计学意义(P〈0.05)。治疗后HAMD评分观察组低于对照组,差异有统计学意义(P〈0.05)。结论:醒神解郁方联合盐酸舍曲林治疗脑卒中后抑郁疗效显著,安全性较好。

英文摘要:

Objective: To observe the clinical efficacy of Xingshen Jieyu tang combined with sertraline hydrochloride in the treatment of post-stroke depression (PSD). Methods: Sixty PSD cases were randomly divided into the observation group(30 cases)and the control group (30 cases). The observation group was given Xingshen Jieyu tang combined with sertraline hydrochloride, and the control group was given sertraline hydrochloride. The treatment course lasted for 6 weeks. Clinical efficacy and the scores of Hamilton rating scales for depression(HAMD) were observed. Results: The total effective rate was 86.70% in the observation group, and was 70.00% in the control group, the difference being significant(P〈 0.05). The scores of HAMD in both groups after treatment were significantly lower than those before treatment, and those scores after treatment of the observation group were lower than those of the control group(P 〈 0.05). Conclusion. Xingshen Jieyu tang combined with sertraline hydrochloride is effective and safe in the treatment of PSD.

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期刊信息
  • 《淮南职业技术学院学报》
  • 主管单位:安徽省教育厅
  • 主办单位:淮南职业技术学院
  • 主编:周国良
  • 地址:安徽淮南市田家庵区林场路1号淮南职业技术学院
  • 邮编:232001
  • 邮箱:hnxbwq@163.com
  • 电话:0554-6647426 6656907
  • 国际标准刊号:ISSN:1671-4733
  • 国内统一刊号:ISSN:34-1241/Z
  • 邮发代号:
  • 获奖情况:
  • 2013年安徽省新闻出版局、教育厅组织的三优评比“...,2012年全国高职高专优秀学报
  • 国内外数据库收录:
  • 被引量:2995