中文摘要：

瞬时受体电位通道（TRP channels）是位于细胞膜上的一类重要的阳离子通道超家族。根据氨基酸序列的同源性，将已发现的28种哺乳动物TRP通道分为：TRPC、TRPV、TRPM、TRPA、TRPP和TRPML6个亚家族。所有的TRP通道都具有6次跨膜结构域。不同的TRP通道对钙离子和钠离子选择性不同。TRP通道分布广泛，调节机制各异，通过感受细胞内外环境的各种刺激，参与痛温觉、机械感觉、味觉的发生和维持细胞内外环境的离子稳态等众多生命活动。

英文摘要：

The transient receptor potential （TRP） superfamily of ion channels comprises 28 members of cation-selective ion channels in Mammalian. On the basis of amino acid sequence homology, TRP channels are grouped into six subfamilies （TRPC, TRPV, TRPM, TRPA, TRPP, and TRPML）. All TRP channels have six predicted transmembrane segments in structure, and different selection for calcium and sodium in permeance. TRP channels are also widespread and activated by multiple stimuli. Meanwhile, as the sensor to the changes in cellular local environments, TRP channels have diverse functions, including thermal, mechanical and taste sensing, as well as maintaining ion homeostasis.