中文摘要：

目的探讨女性乳腺癌术后复发风险的时间分布规律。方法对1996年1月1日～2008年12月31日期间在某市四家＂三甲＂医院手术治疗的女性乳腺癌患者进行随访,并应用生存分析的方法分析术后复发风险。结果单因素和多因素生存分析均提示,腋下淋巴结转移和肿瘤直径较大是乳腺癌术后复发的危险因素（P〈0.05）。复发风险时间曲线呈现双峰型,分别出现在术后第2年和第5年,在有腋下淋巴结转移及肿瘤直径较大的患者中叠加效应更为明显。结论根据患者的特征制定个性化的术后随访和辅助治疗策略,将有助于预防乳腺癌的术后复发。

英文摘要：

Objective To explore the time distribution of recurrence hazard for female breast cancer patients undergoing surgery.Methods The female breast cancer patients were followed up,who underwent surgery from Jan 1,1996 to Dec 31,2008 in four hospitals.Survival analysis was used to study the recurrence hazard.Results Both univariate and multivariate survival analysis indicated that axillary lymphatic metastasis and tumor with larger diameter were risk factors of recurrence（P0.05）.Annual recurrence hazard curve showed a notable peak in the 2nd years,as well as in the 5th years.The stacked effect of double-peak of recurrence hazard curve was more obvious in patients with axillary lymphatic metastasis and larger diameter tumor simultaneously.Conclusion According to the distribution of recurrence hazard,individual strategies for post-operative treatment and follow-up should be formulated in order to prevent the recurrence.