目的:评价5分钟坐立试验(5MssT)在慢性心力衰竭中的应用,以及5MSST与6分钟步行试验(6MWT)等其他心肺功能指标之间的相关性。方法:对30例健康对照组与30例慢性心衰组受试者的5MSST、6MWT进行分析研究;并比较这两种测试对受试者心率、收缩压、舒张压、Borg指数和血氧饱和度的影响。结果:慢性心衰组与健康对照组之间5mln坐立次数和6min步行距离的差异均有显著性意义(P〈0.01)。5MSST和6MwT测试对慢性心衰患者的Borg指数均有明显影响(P〈0.01);而慢性心衰患者只有6MWT测试后心率、收缩压和血氧饱和度出现明显变化(P〈0.05)。慢性心衰组和健康对照组5MSST与6MWT之间的相关系数分别为0.76(P〈0.01),0.51(P〈0.01),具有显著差异。慢性心衰组患者5MSST与年龄和EF值之间的相关系数分别为-0.87(P〈0.01),-0.65(P〈0.01);6MWT与年龄和EF值之间的相关系数分别为-0.65(P〈0.01),-0.77(P〈0.01);健康对照组5MSST和6MWT与年龄之间的相关系数分别为-0.48(P〈0.01),-0.57(P〈0.01),具有显著性差异。结论:5MSST与6MWT呈显著正相关,并且对受试者心率、血压和氧饱和度等心肺活动指数影响较小,可以便捷、准确地评价慢性心力衰竭患者运动耐量,是一种值得推广的简便易行的心肺功能评估方法。
Objective: To discuss the utility of 5-minutes-sit-to-stand test (5MSST) compared to the 6min walking test (6MWT) for the evaluation of functional status in patients with chronic heart failure (CHF). Method: Thirty patients with CHF [mean age (59.7±8.7)years, mean body mass index 23±5] and thirty healthy individuals [mean age (61.3±7.0)years and mean body mass index 24±4] were included in this study. Function- al performance was evaluated by 5MSST and 6MWT. Before the tests, the ejection fraction (EF) was detected. Before and after the tests, heart rate, blood pressure, severity of dyspnea (by Borg scale) and the pulsed oxy- gen saturation (SpO2) were measured. The relationship between 5MSST and 6MWT was analyzed. Result: The results of 5MSST and 6MWT were lower in patients with CHF than that in healthy individuals (P〈0.01). The rise in heart rate, systolic blood pressure and the decrease in SpO2 were statistically significant during the 6MWT in patients with CHF (P 〈 0.05). However, there was significant difference in Borg scale dur- ing both 5MSST and 6MWT in patients with CHF (P〈0,01). The 5MSST and 6MWT were strongly correlat-ed with each other in both groups (P〈 0.01). Similarly, they were correlated with age and ejection fraction in patients with CHF (P 〈 0.01), and were correlated with age in healthy individuals (P 〈 0.01). Conclusion: Similar to 6MWT, 5MSST is also able to determine the functional state correctly in patients with CHF. Additionally, it is easier to apply and more sensitive for the patient's clinical status compared to 6MWT. That is to say, 5MSST can be used as an alternative tool of 6MWT in patients with CHF.