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Preliminary biocompatibility evaluation of regenerated Antheraea yamamai Silk Fibroin in vitro
  • ISSN号:1000-2413
  • 期刊名称:Journal of Wuhan University of Technology-Material
  • 时间:2012.12
  • 页码:1044-1048
  • 分类:TS149[轻工技术与工程—纺织材料与纺织品设计;轻工技术与工程—纺织科学与工程] TQ174.75[化学工程—陶瓷工业;化学工程—硅酸盐工业]
  • 作者机构:[1]National Engineering Laboratory for Modern Silk, College of Textile and Clothing Engineering, Soochow University, Snzhou 215123, China
  • 相关基金:Funded by the National Natural Science Foundation of China ( Nos. 51173125 and 51075422) the Natural Science Foundation of Jiangsu Province of China (Nos. BK2009147 and BK2010253) the Development Foundation of Suzhou of China (No.SYG201001) the Priority Academic Program Development of Jiangsu Higher Education Institutions [PAPD]
  • 相关项目:家蚕丝素蛋白凝聚态结构调控及细胞功能相关性基序研究
中文摘要:

学习试图调查 Sprague Dawley (SD ) 白化体老鼠骨头的粘附,形态学和增长由转换显微镜,数的房间, MTT 测试和扫描共焦的 microscop (LSCM ) 的激光的导出髓的间充质的干细胞(BMSC ) 。在改革 A yamamai SF 电影或混合电影上,房间形态学在骨胶原上几乎与那一样(骨胶原类型我)电影,房间粘附率在 1 h 以后在塑料房间板和 B mori SF 电影上比那高( p < 0.01 )文化,和房间,增长在骨胶原电影上比那显著地高( p < 0.01 )并且塑料房间板( p < 0.01 ),并且更好显然也在 B mori SF 上比那拍摄。在另一方面,在改革 A yamamai SF 多孔的支架的 BMSC 的生存能力在 B mori SF 多孔的支架和医药等级比那好聚乙烯化合物的白酒(PVA ) 海绵。

英文摘要:

The study aimed to investigate the adhesion, morphology and proliferation of Sprague Dawley (SD) albino rat bone marrow-derived mesenchymal stem cells (BMSCs) by inverted microscope, cell counting, MTT test and laser scanning confocal microscop (LSCM). On the regenerated A yamamai SF film or blend films, the cell morphology was almost the same as that on collagen (collagen type I) film, the cell adhesion rate was higher than that on plastic cell plate and B mori SF film after 1 h (p 〈 0.01) of culture, and the cell proliferation was significantly higher than that on collagen film (p 〈 0.01) and plastic cell plate (p 〈 0.01), and also obviously better than that on B mori SF film. On the other hand, the viability of BMSCs in the regenerated A yamamai SF porous scaffold was better than that in B mori SF porous scaffold and medical grade polyvinyl alcohol (PVA) sponge.

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期刊信息
  • 《武汉理工大学学报:材料科学英文版》
  • 中国科技核心期刊
  • 主管单位:
  • 主办单位:武汉理工大学
  • 主编:
  • 地址:武汉市洪山区珞狮路122号
  • 邮编:430070
  • 邮箱:jwutms@mail.whut.edu.cn
  • 电话:027-87384113 87651870
  • 国际标准刊号:ISSN:1000-2413
  • 国内统一刊号:ISSN:42-1680/TB
  • 邮发代号:38-78
  • 获奖情况:
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  • 被引量:149