中文摘要：

目的：分析不同血压参数与原发性高血压（EH）伴微量白蛋白尿（MAU）的相关性。方法：选取51例EH合并MAU患者作为MAU组,选取同期51例EH未合并MAU患者作为NMAU组,对两组患者的一般临床资料、血液生化指标、血压相关指标及其相关性进行比较和分析。结果：NMAU组患者的诊室血压分级显著低于MAU组（P〈0.05）,两组患者除昼间舒张压外的各项血压相关指标的差异均有统计学意义（P〈0.05）。多元线性回归结果显示：患者的MAU水平与中心动脉收缩压（β=0.306）、中心动脉脉压（β=0.215）、臂踝动脉脉搏波传导速度（β=0.163）呈正相关关系（P〈0.05）,与夜间平均动脉压下降率（β=-0.191）呈负相关有关系（P〈0.05）。结论：EH伴发MAU患者主要表现为血压水平的显著升高,特别是中心和肢端收缩压、脉压的升高和昼夜血压节律性的缺失,上述血压变化促进了MAU的发病和进展,血压参数可作为预测EH患者伴发MAU发病和进展的辅助指标。

英文摘要：

Objective： To analyze the correlations of various parameters of blood pressure with essential hypertension （EH） complicated with microalbuminuria （MAU）. Methods： 51 cases of patients with EH complicated with MAU were selected as MAU group and 51 cases of patients with EH who were not complicated with MAU were selected as NMAU group. The general clinical data, blood biochemical index, blood pressure related indexes and their correlation of the patients in the two groups were compared and analyzed. Results： The classification of clinic blood pressure of the patients in the NMAU group was significantly lower than that in MAU group （u=3.374, P〈0.05）. The differences of the blood pressure related indexes except for diastolic blood pressure blood in daytime of the patients between the two groups were statistically significant （t=-3.467-8.168, P〈0.05）. The multiple linear regression analysis showed the central aortic systolic pressure （β=0.306）, the center arterial pulse pressure （β=0.215）, the brachial ankle pulse wave conduction velocity （β=0.163） were positively correlated with the level of MAU of the patients （P〈0.05）, while the night mean blood pressure fall rate （β=-0. 191） was negatively correlated with the level of MAU of the patients （P〈0.05）. Conclusions： The patients with EH complicated with MAU mainly manifested as the significantly elevated blood pressure levels, especially the increases of central and limb systolic blood pressure and pulse pressure as well as the absence of the circadian rhythm of the blood pressure change, which could promote the pathogenesis and development of MAU. The parameters of blood pressure can be used as the auxiliary indexes to predict the incidence and progression of EH complicated with MAU.