中文摘要：

本试验利用Illumina OvineSNP50 Bead Chip芯片对71只苏尼特羊进行了分型,共检测到134个拷贝数变异区域（copy number variation regions,CNVR）,大小范围为29.48kb～1.30Mb之间,总长度达到25.95Mb。基因注释及功能分析结果显示,这些基因与嗅觉感官知觉、化学刺激的感官知觉、感官知觉、识别等环境应答有关。选取5个CNVR进行qPCR验证,其中3个CNVR得到验证。通过对苏尼特羊基因组拷贝数变异的分析可以进一步了解绵羊基因组结构的特点,为今后开展绵羊基因组结构变异与重要经济性状的关联研究提供参考。

英文摘要：

In this study,71 Sunite sheep were genotyped using Illumina OvineSNP50 Bead Chip array,a total of 134CNV regions（CNVR）across the genome were identified,which covered 25.95Mb of the sheep genome.CNVR size on autosomes range from 29.48kb to 1.30Mb.Functional indicated that the most genes overrepresented in environmental responses,which involved in sensory perception of smell,sensory perception of chemical stimulus,sensory perception,cognition.To confirm these findings,quantitative PCR（qPCR）was performed for 5CNVR and 3 of them were successfully validated.Our findings would be of help to underst and the sheep genome and provide preliminary foundation for investigating the association between important economic traits and CNV.