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Discovery of a novel inhibitor of NAD(P)(+)-dependent malic enzyme (ME2) by high-throughput screenin
ISSN号:1671-4083
期刊名称:Acta Pharmacologica Sinica
时间:2014.5
页码:674-684
相关项目:代谢性疾病药物药理学
作者:
Gao, Jing|Li, Jing-ya|Hu, Li-hong|Li, Jia|
同期刊论文项目
代谢性疾病药物药理学
期刊论文 84
同项目期刊论文
5 '-AMP-activated protein kinase (AMPK) regulates progesterone receptor transcriptional acti
Development of Novel Alkene Oxindole Derivatives As Orally Efficacious AMP-Activated Protein Kinase
Synthesis and biological evaluation of novel thiadiazole amides as potent Cdc25B and PTP1B inhibitor
Identification of a new bis-amino acid glycoside selectively toxic to multiple myeloma cells
Azoxystrobin, a mitochondrial complex III Q(o) site inhibitor, exerts beneficial metabolic effects i
Design, synthesis and biological evaluation of 4-fluoropyrrolidine-2-carbonitrile and octahydrocyclo
One-step 'click engineering' considerably ameliorates the practicality of an unqualified r
Discovery, synthesis, and structure activity relationships of 20(S)-protopanaxadiol (PPD) derivative
Curcusone D, a novel ubiquitin-proteasome pathway inhibitor via ROS-induced DUB inhibition, is syner
Novel Small-Molecule AMP-Activated Protein Kinase Allosteric Activator with Beneficial Effects in db
CuAAC Click Chemistry Accelerates the Discovery of Novel Chemical Scaffolds as Promising Protein Tyr
Novel Small-Molecule PGC-1 alpha Transcriptional Regulator With Beneficial Effects on Diabetic db/db
Novel Small-Molecule PGC-1α Transcriptional Regulator With Beneficial Effects on Diabetic db/db Mice
4-Quinolone-3-carboxylic acids as cell-permeable inhibitors of protein tyrosine phosphatase 1B
1H-2,3-Dihydroperimidine Derivatives: A New Class of Potent Protein Tyrosine Phosphatase 1B Inhibito
Regio- and Diastereoselective Construction of α-Hydroxyl-δ-Amino Esters Derivatives via 1,4-Conjugat
Synthesis and biological evaluation of novel 2,3-pyrazole ring-substituted-4,4-dimethyl lithocholic
Design, Synthesis and Biological Activity Evaluation of 2,5-Diphenyl-1,3,4-oxadiazole Derivatives as
Discovery, synthesis, and structure-activity relationships of 20(S)-protopanaxadiol (PPD) derivative
2-(3-Benzoylthioureido)-4,5,6,7-tetrahydrobenzo[b]
Hepatoma-selective imaging of heavy metal ions using a 'clicked' galactosylrhodamine
Design, synthesis and biological evaluation of peptidyl epoxyketone proteasome inhibitors composed o
Design, synthesis and biological evaluation of novel tripeptidyl epoxyketone derivatives constructed
Probing disease-related proteins with fluorogenic composite materials
Discovery of a novel inhibitor of NAD(P)+-dependent malic enzyme (ME2) by high-throughput screening
Design, synthesis and biological evaluation of 4-anilinothieno[2,3-d] pyrimidine-based hydroxamic ac
A novel chemical uncoupler ameliorates obesity and related phenotypes in mice with diet-induced obes
Design, synthesis and biological evaluation of 4-fluoropyrrolidine- 2-carbonitrile and octahydrocycl
Design, synthesis and biological evaluation of hetero-aromatic moieties substituted pyrrole-2-carbon
New Isoprenylated Phenolic Compounds from Morus laevigata
Glycosylation enhances the aqueous sensitivity and lowers the cytotoxicity of a naphthalimide zinc i
5'-AMP-activated protein kinase (AMPK) regulates progesterone receptor transcriptional activ
Synthesis of novel 3-aryl-1-oxa-2,8-diazaspiro[4.5]dec-2-ene derivatives and their biological evalua
Synthesis and characterization of 5,7-dihydroxyflavanone derivatives as novel protein tyrosine phosp
Novel Small-Molecule AMPK Activator Orally Exerts Beneficial Effects on Diabetic db/db Mice
Revisit of a dipropargyl rhodamine probe reveals its alternative ion sensitivity in both a solution
Synthesis and Biological Evaluation of Furan-chalcone Derivatives as Protein Tyrosine Phosphatase In
Physalin B not only inhibits the ubiquitin-proteasome pathway but also induces incomplete autophagic
Synthesis and biological evaluation of 4,4-dimethyl lithocholic acid derivatives as novel inhibitors
Synthesis and biological evaluation of 2,4,6-Trihydroxychalcone derivatives as novel protein tyrosin
Synthesis and structure-activity relationship of non-phosphorus-based fructose-1,6-bisphosphatase in
Design and synthesis of paracaseolide A analogues as selective protein tyrosine phosphatase 1B inhib
Mixed galactolipid anomers accentuate apoptosis of multiple myeloma cells by inducing DNA damage
Disruption of the unfolded protein response (UPR) by lead compound selectively suppresses cancer cel
Design, synthesis and biological evaluation of isoquinoline-based derivatives as novel histone deace
Curcusone D, a novel ubiquitin-proteasome pathway inhibitor via ROS-induced DUBs inhibition, is syne
Synthesis and biological evaluation of novel bis-aromatic amides as novel PTP1B inhibitors
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Substitution Pattern Reverses the Fluorescence Response of Coumarin Glycoligands upon Coordination w
Design, Synthesis, and Biological Evaluation of Novel 2-Ethyl-5-phenylthiazole-4-carboxamide Derivat
PTP1B inhibitors from stems of Angelica keiskei (Ashitaba)
Azoxystrobin, a mitochondrial Complex III Qo site inhibitor, exerts beneficial metabolic effects in
2-(3-Be nzoylth iou reido)-4,5,6,7-tet ra hydro be n zo [b ] thiophene-3-carboxylic acid ameliorates metabolic disorders in high-fat diet-fed mice
含3,4-二氢-2(1H)-喹啉酮结构查尔酮衍生物的合成及蛋白酪氨酸磷酸酯酶1B抑制活性研究
(E)-1-取代苯基-3-[4-((E)-(2-(4-苯基噻唑-2-基)腙)甲基)苯基]-2-丙烯-1-酮的合成及PTP1B抑制活性研究
期刊信息
《中国药理学报:英文版》
中国科技核心期刊
主管单位:中国科学技术协会
主办单位:中科院上海药物研究所
主编:丁光生
地址:上海市太原路294号31号楼
邮编:200031
邮箱:
电话:021-54922821 54922822
国际标准刊号:ISSN:1671-4083
国内统一刊号:ISSN:31-1347/R
邮发代号:4-295
获奖情况:
1992、1996年两届全国优秀科技期刊一等奖,1992、1996、1997年中国科协、中科院以及上海市优...,首届国家期刊奖、2000年中科院优秀期刊评比特别奖
国内外数据库收录:
俄罗斯文摘杂志,美国化学文摘(网络版),英国农业与生物科学研究中心文摘,波兰哥白尼索引,荷兰文摘与引文数据库,荷兰医学文摘,美国生物医学检索系统,美国剑桥科学文摘,美国科学引文索引(扩展库),美国生物科学数据库,日本日本科学技术振兴机构数据库,中国中国科技核心期刊,英国食品科技文摘,中国北大核心期刊(2000版)
被引量:1239