中文摘要：

目的探讨3．0T术中磁共振成像（iMRI）导航在神经外科手术应用的临床价值。方法回顾性分析2010年9月至2011年3月，在具备诊断和手术功能的“3．0TiMRI数字一体化神经外科手术中心”施行的各类颅脑手术122例，包括临床资料、iMRI实时影像导航对手术进程和手术结果的影响等。结果122例患者手术室内扫描2—4次，平均2．6次。各种扫描图像质量皆优良。iMRI技术使脑胶质瘤（60例）手术全切除率从71．7％提高到90．0％，患者的近期致残率为6．7％，远期致残率3．3％。iMRI技术使垂体大腺瘤（29例）手术全切除率从75．9％提高到93．1％。未发生与应用iMRI数字一体化神经外科手术有关的并发症（如感染等）。同期完成2500余人次MRI诊断性检查。结论3．0TiMRI神经导航的应用，为脑胶质瘤与垂体大腺瘤手术进程的实时引导、切除范围的精确判断以及脑功能与代谢信息的定量分析提供了客观依据，真正实现了脑肿瘤的最大程度安全切除。

英文摘要：

Objective To report the preliminary experience in clinical application of 3.0 T intraoperative magnetic resonance imaging （iMRI） neuronavigation system in China. Methods From September 2010 to March 2011, a consecutive series of 122 patients with intracranial lesions underwent operations in guidance with 3.0 T iMRI. A retrospective analysis was conducted regarding clinical efficiency. Results Among 122 procedures, the numbers of intraoperative scanning were 2-4 times with an average of 2. 6. The qualities of images were excellent. Due to the discovery and further possibility of resection of residual tumors, the ratio of gross total resection was increased from 71.7% to 90. 0% in cerebral gliomas（n =60）, while from 75.9% to 93.1% in macroadenomas （n =29）. There were 6. 7% of all patients occurred postoperative paralysis, but only 3.3% of patients had persistent paralysis at 1-2 months follow-up. There was no iMRI-related adverse event occurred. During the same period, more than 2500 patients underwent diagnostic MRI scanning. Conclusions 3.0 T iMRI neuronavigation system provides high-quality intraoperative structural, functional and metabolic images for real time tumor resection control and accurate functional preservation, resulting in an improvement in maximal safe brain surgery. The system is cost-effective.