中文摘要：

象墙那样的血液动力学的因素砍压力玩在服的动脉瘤的致病和处理的一个重要角色。在现在的学习，我们与二种不同组成的关系在服的动脉瘤上使用计算液体结构相互作用分析让动脉瘤的墙以便调查动脉瘤的墙的效果模拟结果上的机械性质。我们由使用位于 Willis 的圆的不同分支的不同尺寸的服的动脉瘤的二个病人特定的模型执行这些分析。模型从 3D 被构造旋转 angiography 图象数据和血流动动力学在流入的生理的联盟者代表波形下面被学习。从在这调查分析的耐心的模型，我们发现服的动脉瘤的变丑是很小的。但是由于 Navier 的非线性的特性司烧方程，这些小变丑能在流动特征上有重要影响。另外，我们发现动脉瘤墙的机械性质在动脉瘤的变丑分发上有大效果，它也影响墙砍压力分发和流动模式。因此，怎么定义为动脉瘤的墙的一种合适的组成的关系应该在血液动力学的模拟小心地被考虑。

英文摘要：

Hemodynamic factors such as the wall shear stress play an important role in the pathogenesis and treatment of cerebral aneurysms. In present study, we apply computational fluid-structure interaction analyses on cerebral aneurysms with two different constitutive relations for aneurismal wall in order to investigate the effect of the aneurismal wall mechanical properties on the simulation results. We carry out these analyses by using two patient-specific models of cerebral aneurysms of different sizes located in different branches of the circle of Willis. The models are constructed from 3D rotational angiography image data and blood flow dynamics is studied under physiologically representative waveform of inflow. From the patient models analyzed in this investigation, we find that the deformations of cerebral aneurysms are very small. But due to the nonlinear character of the Navier-Stokes equations, these small deformations could have significant influences on the flow characteristics. In addition, we find that the aneurismal-wall mechanical properties have great effects on the deformation distribution of the aneurysm, which also affects the wall shear stress distribution and flow patterns. Therefore, how to define a proper constitutive relation for aneurismal wall should be considered carefully in the hemodynamic simulation.