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山地团进攻制式火炮打击兔应激防护模型血清自由基变化实验研究
  • ISSN号:1671-4695
  • 期刊名称:《临床和实验医学杂志》
  • 时间:0
  • 分类:R285.5[医药卫生—中药学;医药卫生—中医学]
  • 作者机构:[1]解放军第一七五医院暨厦门大学附属东南医院妇儿科,福建漳州363000, [2]解放军73131部队,福建漳州363000, [3]解放军第一七五医院暨厦门大学附属东南医院神经外科,福建漳州363000
  • 相关基金:基金项目:1.全军十一五医学科研基金面上项目(06MB152);2.国家自然基金面上项目(30672167);3.福建省科技计划青年人才项目(2006173150);4.福建省漳州市科技计划项目(Z06078)资助.本文内容经所在单位保密委员会审核通过.
中文摘要:

目的探讨战场火炮覆盖应激后,不同位置掩体内兔血清自由基变化规律。方法闽南山地秋季团进攻演习中,根据隐蔽住置设置实验兔空白对照组、反角隐蔽组和迎面角隐蔽纽。基数火炮覆盖应激刺激后6h,存活兔检测血清氧自由基含量,进行统计学比较。结果与空白对照组比较,反角隐蔽组和迎面角隐蔽组一氧化氮(NO)与诱导型一氧化氮合酶(iNOS)的含量显著升高(P〈0.01),总超氧化物歧化酶(TSOD)的含量明显降低(P〈0.01),差异具有统计学意义。与反角近距隐蔽组相比,迎面近距隐蔽组NO显著升高(P〈0.01),TSOD显著降低(P〈0.01),差异具有统计学意义。结论火炮打击后实验兔应激反应强烈,不同位置掩体对存活及血清自由基含量影响显著。

英文摘要:

Objective The changes in rule of serum free radicals in rabbits hidden in different position of blindage were studied after the stress of attacking artillery in battlefield. Methods During the autumn regiment attack exercise in South Fujian hilly area, all experimental rabbits were divided into 3 groups ( blank group, reverse hidden group and frontage hidden group) according to their concealed location. Six hours after stress stimulation of artillery, the contents of serum oxygen free radicals in survival rabbits were measured and statistically analyzed. Results The findings in 3 groups were multiply compared. In stress group, the contents of serum iNOS and NO were significantly increased( P 〈0.01 ), but the content of T - SOD was obviously decreased( P 〈0.01 ), and there was significant difference between them. In comparison with reverse hid- den group, contents of serum NO in frontage hidden group were obviously increased( P 〈0.01 ), but the content of T - SOD was obviously de- creased ( P 〈 0.01 ). There was significant difference between them. Conclusion The stress response in all experimental rabbits after striking of artillery is very strong, but different position of blindage can significantly influence their survival and content of serum free radicals.

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期刊信息
  • 《临床和实验医学杂志》
  • 中国科技核心期刊
  • 主管单位:北京市卫生和计划生育委员会
  • 主办单位:首都医科大学附属北京友谊医院
  • 主编:刘建
  • 地址:北京市西城区永安路95号
  • 邮编:100176
  • 邮箱:LCHYX111@163.com
  • 电话:010-63139243
  • 国际标准刊号:ISSN:1671-4695
  • 国内统一刊号:ISSN:11-4749/R
  • 邮发代号:80-494
  • 获奖情况:
  • 国内外数据库收录:
  • 中国中国科技核心期刊
  • 被引量:45659