中文摘要：

以对二茂铁苯甲酸和2-氦基-5-芳基-1,3,4-噻二唑化合物为原料,合成了7个新的二茂铁苯甲酰噻二唑化合物FcL1-FcL7.采用IR、1H NMR和元素分析对化合物进行了表征.用X-Ray单晶衍射测定了化合物FcL4的晶体结构.电化学研究表明,化合物在电极表面发生可逆的单电子转移,FcL1-FcL7对Pb2＋和Zn2＋都有一定的电化学响应.抗菌活性试验表明FcL1-FcL7均对玉米禾谷镰刀菌有较好的抑菌活性和选择性.抗癌活性试验表明FcL5-FcL7对人体食管癌细胞的抑制作用明显.

英文摘要：

Seven kinds of ferrocenyl-benzoyl-thiadiazole compounds FcL_1~FcL_7 were synthesized by using 4-ferrocenylbenzoic and 2-amino-5-aryl-1,3,4-thiadiazole as raw materials.These compounds were characterized by IR,~1H NMR and elemental analysis.The crystal structure of FcL_4 was determined by X-ray diffraction analysis.The electrochemical research showed that the redox reaction on the surface of electrode was reversible with single electron,and FcL_1~FcL_7 have a certain redox response to Pb~（2＋） and Zn~（2＋）.The antibacterial activity tests indicated that FcL_1~FcL_7 presented significant activity and selectivity against Fusarium graminearum.FcL_5~FcL_7 exhibited good inhibition against human esophageal cancer cells in the anticancer activity tests.