线粒体作为真核细胞内一种重要的细胞器,在许多生理病理过程中发挥重要作用。蛋白质组学研究技术的不断发展推动了线粒体蛋白质组的研究。本文对近年来线粒体蛋白质组学的研究现状、存在的影响因素及发展前景进行了综述。
As an important eukaryotic subcellular organelle, the mitochondrion plays an important role in many physiological and pathological processes. The rapid developments in proteomic techniques have promoted the studies of mitochondrial proteomics. As a new science in the era of post-genomics, proteomic techniques provide a very effective approach to explore differentially expressed mitochondrial proteins in various physiological and pathological processes. This article reviews the status, problems and future prospects of recent studies in mitochondrial proteomics.