中文摘要：

目的：比较飞秒激光矫正术（LASIK）与后房型人工晶状体植入术（posterior chamber intraocular lens implantation,ICL）矫治高度近视后的效果。方法：选择2012-02/2015-02在我院接受手术矫正的高度近视患者55例106眼,根据患者实施不同的手术矫正法将其分为观察组和对照组,观察组的患者使用ICL植入术进行矫正治疗（27例53眼）,对照组则使用LASIK治疗（28例53眼）。术后随访1a,分析两组患者的视觉质量、高阶像差与并发症症,并对其进行比较。结果：术后1a,观察组的裸眼视力（uncorrected visual acuity,UCVA）、最佳矫正视力（best corrected visual acuity,BCVA）、有效性指数、安全性指数分别为1.04±0.86（LogMAR）、0.97±0.19（LogMAR）、104.69±18.56、108.79±17.68,明显高于对照组的0.78±0.11（LogMAR）、1.04±0.09（LogMAR）、93.78±15.65、100.71±11.68,差异具有统计学意义（P〈0.05）。且观察组在明暗两种环境下的各个空间频率段的对比敏感度均高于对照组,其中在明环境下1.5、3、6、12c/d与暗环境下1.5、3、6、18c/d,两组患者差异具有统计学意义（P〈0.05）。术后1a观察组的球差和彗差均低于对照组,两组相比较具有统计学差异（P〈0.05）;三叶草像差两组患者比较无统计学差异（P〉0.05）;两组患者均未出现严重的并发症。结论：LASIK和ICL植入术都能够有效地改善患者的视觉质量,但对于高度近视患者而言,ICL植入术的效果更显著,ICL植入术的安全性指数、有效性指数以及视觉质量均优于LASIK。

英文摘要：

AIM ： To study correcting effect and visual quality after laser-assisted in situ keratomileusis（ LASIK） with femtosecond and posterior chamber intraocular lens（ ICL） implantation in high myopia patients.METHODS： Fifty-five patients（ 106 eyes） with high myopia fromFebruary 2012 to February 2015 in our hospital were analyzed. According to the different operation, patients were divided into the observation group（ using ICL implantation,27 cases with 53 eyes） and the control group（ using LASIK,28 cases with 53 eyes）.Postoperative follow-up was 1a,to observe and analyze the visual quality, higher order aberration and complications of two groups.RESULTS： Uncorrected visual acuity（ UCVA）,the best corrected visual acuity（ BCVA）,effectiveness index and security index at 1a postoperatively of observation group,were 1. 04±0. 86（ Log M AR）,0. 97±0. 19（ Log M AR）,104. 69±18. 56,108. 79 ± 17. 68,significantly higher than those of control group 0. 78 ± 0. 11（ Log M AR）, 1. 04 ± 0. 09（ Log MAR）,93. 78±15. 65,100. 71±11. 68（ P0. 05）. And observation group in the two kinds of light and shade environment at various spatial frequency contrast sensitivity were higher than the control group. Those under the light environment at 1. 5,3,6,12 c / d and under dark environment at 1. 5,3,6,18 c / d compared were different between the two groups（ P 0. 05）. Spherical aberration and comatic aberration of observation group at1 a after operation were lower than those of control group（ P 0. 05）. The difference of trefoil between the two groups was not significant（ P 0. 05）. No severe complications were observed in both groups.CONCLUSION： LASIK with femtosecond and ICL lensimplantation can effectively improve the patient＇s visual quality, but for patients with high myopia, ICL lens implantation effect is more significant,the safety index of ICL implantation,as well as the effectiveness index and the visual quality are better than those of LASIK.