中文摘要：

心脏发生是脊椎动物器官发生中的最早进程之一,其重要功能是为机体提供营养和氧气.心管作为最初心脏的功能承载体和心脏的原基,起着至关重要的作用.心管发育过程受多种信号通路的严密调控,研究证实Wnt信号、Notch信号、BMP信号、FGF信号等均参与心管发育的有关过程,介绍动物胚胎早期心管发育过程中的相关信号传导调控机制的研究现状及进展.

英文摘要：

The cardiogenesis is one of the earliest processes in vertebrate organogenesis. The function of heart is to provide nutrients and oxygen for the body. Heart tube,which is the initial functional carrier of the heart,plays a vital role in the embryonic development. The developmen of heart tube is regulated by many kinds of signal pathways such as Wnt signal,Notch signal,BMP signal,FGF signal and etc.This review,we focus on the research process of these signal regulations of heart tube development in recent years.