中文摘要：

目的分析急性脑梗死患者肺部感染病原菌分布及耐药性,为临床预防和控制感染提供参考依据。方法收集2009年1月-2013年8月于医院治疗的66例急性脑梗死发生肺部感染患者临床资料,分析病原菌分布并测定其耐药性,采用SPSS 18.0软件进行统计分析。结果从66例患者的呼吸道分泌物中分离培养出56株病原菌,检出率为84.8%;以革兰阴性菌为主,共38例占67.86%;肺炎克雷伯菌及铜绿假单胞菌对多种常见抗菌药物的耐药率均较高,最高分别为82.35%和80.00%;大肠埃希菌对氨苄西林、头孢他啶、头孢噻肟、庆大霉素及阿米卡星的耐药率均较高,分别为75.00%、25.00%、50.00%、50.00%、25.00%。结论分析急性脑梗死并发肺部感染的病原菌分布及耐药性将有助于指导临床合理应用抗菌药物。

英文摘要：

OBJECTIVE To analyze the distribution of pathogenic bacteria of acute cerebral infarction complicated with lung infections and the situation of drug resistance ,so as to provide theoretical bases for clinical prevention and control .METHODS The clinical data of 66 cases of acute cerebral infarction complicated with lung infection who were treated in the hospital from Jan .2009 to Aug .2013 were collected ,the distribution of pathogenic bacte‐ria was analyzed and the drug resistance was detected .The SPSS 18 .0 software was used for statistical analysis . RESULTS Totally 56 pathogenic bacterial strains were detected from the respiratory secretions （pharyngeal swab or sputum） of 66 patients with the positive rate of 84 .8% ,mainly including gram‐negative bacteria （38 cases , 67 .86% ） .The drug resistance rates of K lebsiella pneumoniae and Pseudomonas aeruginosa were high to most of the common antibacterial drugs ,with the highest resistance up to 82 .35% and 80 .00% ,respectively .The drug resistance of Escherichia coli was high to ampicillin ,ceftazidime ,cefotaxime ,gentamicin and amikacin ,being re‐spectively 75 .00% ,25 .00% ,50 .00% ,50 .00% ,25 .00% .CONCLUSION Analysis of the distribution and drug resistance of pathogenic bacteria of acute cerebral infarction complicated with lung infections will be helpful for guiding the clinical rational use of antibacterial drugs .