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中文摘要：
从镁基生物材料的发展历程、最新进展以及亟待解决的问题等方面进行综述。镁基材料因其具有优良的力学性能、弹性模量接近人骨,同时更具有可降解,降解产物于人体无害,生物相容性好等优点,而被研究人员认为在生物医学材料领域极具应用价值。目前的研究主要集中在硬组织替换和修复以及作为可降解的管腔内支架方面。镁基材料的降解速率与组织痊愈速率不匹配（镁基材料降解过快）是目前限制镁基生物材料在临床应用的首要问题,研究人员通过各种技术手段（热处理、表面改性、镀膜、开发新合金等）来调节镁基材料在体液内的降解速率,取得了一定的进展,但与实际应用仍有很大距离,需要进一步研究和探索。
英文摘要：
This paper reviews the development process of Mg-based biomaterials and existing problems to be solved.The alloys have excellent mechanical properties and low elastic moduli that are closer to natural bones.Moreover,they are degradable and biocompatible.It is believed that Mg-based biomaterials have great potential applications in biomedical field.Present studies are focused on the application in hard tissue replacement and repair,and the minimally invasive cardiovascular therapy.The major inhibition of Mg-based biomaterials in clinical application is that their degradation rates are too fast to match the rates of tissue regeneration.Many techniques have been developed,such as surface modification or coating,development of new alloy,to adjust their degradation rates to match the growth rates of bone tissue in human body.However,there is still a long way to go to meet the requirement of clinical application.More intensive researches are needed.
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