以4-氨基丁酸(4-ABA)为修饰剂,制备了4-ABA修饰碳纳米管掺杂碳糊电极(P-4-ABA/CNTPE),研究了多巴胺(DA)在此修饰电极上的电化学行为,并用于DA的检测。在pH2.0的BR缓冲溶液中,DA在P-4-ABA/CNTPE上产生一对灵敏的氧化还原峰。其氧化峰电流与DA的浓度在8.0×10^-5mol/L~5.3×10^-7mol/L范围内呈良好的线性关系,检测限为2.0×10^-7mol/L。所修饰电极具有较好的重现性、稳定性,对抗坏血酸(AA)和尿酸(UA)具有较好的抗干扰能力。应用于针剂以及人体实际尿样中多巴胺含量的测定,结果令人满意。
Poly 4-aminobutyric acid modified carbon nanotube-doped carbon paste electrode(P-4-ABA/CNTPE)was constructed by electropolymerizing 4-ABA. Voltammetrie behavior of dopamine (DA) was investigated at the modified electrode. In Britton-Robinson(BR) buffer solution( pH 2.0), DA has a pair of sensitive redox peak at the modified electrode, and the oxidation peak current was linearly increased with the concentration of DA in the range of 8.0 × 10-5 mol/L-5.3×10-7 mol/L,with a detection limit of 2.0×10-7 mol/L. The modified electrode exhibited good repeatability, stability and avoided the interference of aseorbic acid (AA) and uric acid (UA). This method was used for the determination of DA in a DA hydrochloride injection and human urine samples with satisfactory results.