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中文摘要：
随着分子生物学及肿瘤免疫学的发展，免疫治疗已逐渐发展成为肿瘤继手术、放疗、化疗、靶向治疗的又一新兴治疗手段，通过封闭免疫检查点分子来阻断某些抑制性信号通路，可以激活机体免疫系统、增强T细胞活性、抑制肿瘤细胞免疫逃逸，继而抑制肿瘤生长，改善患者预后。本文就免疫检查点分子在胶质瘤中的最新研究进展做一综述。
英文摘要：
With the development of molecular biology and tumor immunology, immunotherapy has gradually developed into an important strategy for cancer treatment in recent years, following surgery, radiotherapy, chemotherapy and targeted therapy. By blocking the immune checkpoint molecules to block certain inhibitory signals pathway, it can activate the immune system, enhance T cell activity, inhibit the immune escape of tumor cells, ultimately inhibit tumor growth and improve patient prognosis. In this paper, we would illustrate the reserch progress of immune checkpoint molecules in glioma.
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