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A cellular scale numerical study of the effect of mechanical properties of erythrocytes on the near-wall motion of platelets
  • ISSN号:0567-7718
  • 期刊名称:《力学学报:英文版》
  • 时间:0
  • 分类:S853.61[农业科学—临床兽医学;农业科学—兽医学;农业科学—畜牧兽医] Q592.1[生物学—生物化学]
  • 作者机构:[1]MOE Key Laboratory of Hydrodynamics,Department of Engineering Mechanics,Shanghai Jiao Tong University,200240 Shanghai, China, [2]SJTU-CU ICRC, Shanghai Jiao Tong University,200240 Shanghai, China
  • 相关基金:supported by the National Natural Science Foundation of China(11072155 and 11232010); Doctoral Fund of Ministry of Education of China(20100073120009)
中文摘要:

血小板的近墙的运动上的红血球的机械性质的效果数字地与沉浸的边界方法被学习。房间作为超膜用可以忽略的厚度包围的 viscous-fluid-filled 囊被建模。数字结果证明随分血器的增加,血小板的近墙的来临被提高,与哪个血小板展览它的近墙的踩坦克的运动的更大的变丑和取向角度,和把血小板推到墙的侧面的力量与更大的变化被增加振幅。同时,近墙的来临被增加红血球的僵硬减少。

英文摘要:

The effect of mechanical properties of erythrocytes on the near-wall motion of platelets was numerically studied with the immersed boundary method. Cells were modeled as viscous-fluid-filled capsules surrounded by hyper-elastic membranes with negligible thickness. The numerical results show that with the increase of hematocrit, the near-wall approaching of platelets is enhanced, with which platelets exhibit larger deformation and orientation angle of its near-wall tank-treading motion, and the lateral force pushing platelets to the wall is increased with larger fluctuation amplitude. Meanwhile the near-wall approaching is reduced by increasing the stiffness of erythrocytes.

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期刊信息
  • 《力学学报:英文版》
  • 中国科技核心期刊
  • 主管单位:中国科学技术协会
  • 主办单位:中国力学学会 中国科学院力学研究所
  • 主编:卢天健
  • 地址:北京市海淀区北四环西路15号
  • 邮编:100190
  • 邮箱:actams@cstam.org.cn
  • 电话:010-62536271
  • 国际标准刊号:ISSN:0567-7718
  • 国内统一刊号:ISSN:11-2063/O3
  • 邮发代号:2-703
  • 获奖情况:
  • 国内外数据库收录:
  • 被引量:352