中文摘要：

手性醇具有重要而广泛的应用价值,其不对称制备一直是有机合成领域的研究重点和热点.其中,不对称催化尤其是不对称催化氢化,以其高效、绿色和经济等优势正逐渐在手性醇的工业化制备中显示出巨大的潜能.首次对烯醇酯不对称催化氢化合成手性醇领域进行了综述,全面地介绍了各种结构类型和取代形式烯醇酯的不对称催化氢化研究现状,系统地分析了不同手性配体的过渡金属配合物催化剂的优势与不足,进而从新底物、新配体以及新金属等方面对该领域的发展方向进行了探讨.

英文摘要：

Chiral alcohols are an important class of compounds and possess a broad array of applications, thus their asymmetric preparation is an important area of research in the field of organic synthesis. Amongst methodologies for the preparation of such compounds, catalytic asymmetric hydrogenation has gained widespread interest due to its efficiency, environmentally friendliness and economic advantages, and is gradually becoming a technology with great potential for the industrial preparation of chiral alcohols. This review provides the first overview for the catalytic asymmetric hydrogenation of enol esters for the synthesis of chiral alcohols. A comprehensive and up-to-date introduction are given for a number of different substrates. A thorough analysis is provided concerning the advantages and disadvantages of different chiral ligands and their transition-metal complexes. Finally, a brief discussion relating to developments and potential areas of further research concerning new substrates, new ligands and new catalytic metals, is presented.