中文摘要：

目的 通过系统综述和Meta分析了解我国轻度认知功能障碍（mild cognitive impairment,MCI）的患病率情况.方法 制定检索策略和纳入排除标准,检索中国生物医学文献数据库（China biology medicine disc,CBMdisc）、中国期刊全文数据库（China national knowledge infrastructure,CNKI）、维普数据库（VIP database,VIP）、万方数据库、PubMed、荷兰医学文摘数据库（excerpta medica database,EMBASE）、the cochrane library等中英文数据库,采用观察性研究质量评价标准对纳入文献质量进行评价.利用,衡量研究间的异质性大小,选择相应模型进行定量合并患病率并进行亚组分析.结果 纳入相关文献40篇,文献总体质量较好（总得分中位数为15分）.经Meta分析合并后所得MCI患病率为14.5％ （95％CI12.8％～16.2％）,亚组分析结果显示近年来MCI患病率随时间逐步升高,随年龄增加患病率升高,女性高于男性[16.0％ （95％CI 14.2％～17.9％）与12.6％（95％CI 10.8％～14.4％）],农村高于城市[18.2％（95％CI 14.2％～22.1％）与13.6％ （95％CI 11.9％～15.3％）],而文化程度升高患病率下降,独身（包括未婚、离异或独居）老年人患病率高于已婚者.结论 MCI在我国患病率较高,且在年龄、性别、受教育程度、婚姻状况、居住地等因素间存在差异.

英文摘要：

Objective To understand the prevalence of mild cognitive impairment（MCI） and to compare the geographical distribution for the early prevention and treatment of disease,and to provide the reference basis for the establishment of related policies.Method Systematical search method and inclusion criterion were made and relative English and Chinese database such as China biology medicine disc （CBMdisc）,China national knowledge infrastructure （CNKI）,VIP database （VIP）,WanFang,Pubmed,excerpta medica database （EMBASE）,the cochrane library were searched.Tailored quality evaluation standard of epidemiological research was used to evaluate study quality for each included study.I2 was used to measure the heterogeneity between studies,and relevant model of meta-analysis and subgroup analysis were carried out to merger and analyze data.Subgroup analysis was used to explore heterogeneity.Results Overall,in the present 40 relevant articles were included.The quality assessment was good （median score was 15）.Meta-analyses were conducted for 40 cross-sectional studies investigating the prevalence of MCI,the pooled prevalence of MCI was 14.5％ （95％CI 12.8％-16.2％）.Subgroup results showed that in recent years,the prevalence rate has been gradually increased over time.There was a higher prevalence in those who were older.The prevalence rate of female were higher than that of male（16.0％（95％CI 14.2％-17.9％） vs.12.6％（95％CI 10.8％-14.4％））,rural were higher than that of urban （18.2％（95％CI 14.2％-22.1％） vs.13.6％ （95％ CI 11.9％-15.3％））.Prevalence was decreased while cultural level rising,and that of single （including single,divorce or live alone） elderly was higher than married people.Conclusion MCI in China have a high prevalence.Over the past decade,the prevalence and incidence of MCI were significantly affected by age,gender,education level,marital status,place of residence and other factors.