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中文摘要：
以3-氯苯丙酮为起始原料,经不对称还原、烃化、O-甲磺酰化、SN2二甲胺化和成盐合成了盐酸达泊西汀,总收率39.9%,其结构经1H NMR和MS确证。
英文摘要：
Dapoxetine hydrochloride was synthesized from 3-chloropropiophenone by catalytic asymmetric reduction,alkylation,O-methlsulfonylation,SN2 dimethylamination,as well as salt formation in an overall yield of 39.9%.The structure was confirmed by 1H NMR and MS.
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